Searchable abstracts of presentations at key conferences in endocrinology

ea0031p39 | Clinical biochemistry | SFEBES2013

Cross-reactivity of ten recombinant insulin preparations in the Abbott Architect Insulin immunoassay

Clarke Catriona , Shearing Catherine

Preparations of recombinant insulin and insulin analogues are used in the treatment of insulin-dependent diabetes. Recombinant insulin that corresponds to the human sequence might be expected to cross-react extensively with insulin assays. Insulin analogues contain modifications that alter their action profiles and may therefore interact unpredictably with detection antibodies. In the differential diagnosis of hypoglycaemia it is important to be aware of the extent of the cros...